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Zoya Demidenko: Scientist in Oncology Biology
Zoya Demidenko is a prominent scholar affiliated with the Division of Cell Stress Research at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Earlier, she worked at the National Institutes of Health and New York Medical College, building a robust background in clinical research.
Demidenko's scholarly contributions encompasses several pivotal areas, including the PI3K/AKT/mTOR molecular pathway, cell cycle control, biological aging, and malignancy science. As of now, she has authored more than 46 peer-reviewed publications, which have received upwards of 4,100 citations — a testament to the significance of her findings.
Among her most notable contributions involves explaining the mechanisms of cell aging. Her work showed that when the cell cycle is halted but cellular expansion proceeds, the cells experience senescence. Significantly, Zoya Demidenko showed that this process can be inhibited by medication using agents such as rapamycin.
Zoya Demidenko has also brought considerably to oncological therapy research, notably in the domain of cyclotherapy — a strategy intended to protecting healthy tissue from anticancer drugs whilst leaving malignant cells susceptible. This method carries considerable promise for diminishing the toxic effects of cancer treatment.
Throughout her professional journey, Demidenko has partnered with top scientists worldwide, such as Dr. Mikhail Blagosklonny. Her work appears in prestigious publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
Holding an h-index of 33, Zoya Demidenko stands as a highly impactful figure in current oncological science, with her findings keep to shape our knowledge of the way biological cells grow old, interact with therapy, and the ways in which cancer can be more effectively targeted.
https://moodylab.smhs.gwu.edu/lab-members

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